Lymphatic Drainage and Peripheral Tolerance in Children

Lymphatic Drainage and Peripheral Tolerance in Children

Lymphatic drainage is essentially the process wherein fluid from infected tissues drain to localized lymph nodes in the lower portion of the body. This fluid carried by the lymphatic fluid carries toxic elements of the human metabolism, remaining toxins, and foreign infectious agents. This process is called lymphatic drainage or lymphatic filtration. The lymphatic system eliminates large volume of fluid during the regular daily activity of your system and stores it in the body's cells for the future use. This fluid-absorbing process occurs through the body, not only in the lungs, spleen, liver and kidney.

The major benefit of lymphatic drainage is that it is beneficial to the whole body health. Lymphatic fluids carry away bacteria, virus, cells and other abnormal cells which may influence the function of the immune system. These abnormal cells are removed through the lymphatic drainage system to the sites of treatment. With the normal functioning of the immune system, the spread of disease-causing organisms is prevented.

A health practitioner who specializes in diagnosis and treatments of diseases like cancer, HIV/AIDS, leukemia and lymphoma can do a lung biopsy for a lung allograft. This is a procedure in which a small incision is made from the lung. The doctor collects a sample of lung tissue and then constructs an artificial body from the accumulated material. After completing this procedure, the doctor reconstructs the patient's body via new artificial lung using a procedure called lymphatic drainage.

Lung cancer and chronic pulmonary (CPR) diseases are diseases which can be treated through lung allografts. Lung cancer is a tumor that has spread into the tissues of the lungs or other areas of the body. In cases like this, the disease has spread into the portion of the body that receives air through breathing. In terms of the CPR disease, it's a disorder in which a man has been resuscitated after being placed into respiratory arrest. Although this is a fantastic example of a disease process, it still demonstrates the importance of lymphatic drainage. This is because the lungs were formerly described as having a"crawl space," where germs had a chance to breed since there wasn't a significant amount of oxygen supply.

At these times, the lung tissues become the perfect place for infectious agents to replicate. Once infectious agents reproduce in this environment, it becomes impossible to fight off the invading organisms and the disease process can then progress. Luckily, the lung cells do not become a good place for bacteria to reproduce. This is the reason a lung lymphatics transplant may be used in combination with a previously described pulmonary grafts.

A pulmonary graft is essentially a tissue from one part of the body is transplanted onto the areas of the lungs which are infected. The grafts are typically taken in the patient's own lymphatic system or the umbilical cord, although patients may also be given tissue from another person's body if this is preferable. This permits the immune cells to enter the contaminated area with no problems that might develop because of rejection by the neighboring tissue.


After the grafts are implanted, the new lymphatics can make a continuous journey toward the heart. During this journey, the lymphatic fluids collect and go down the pulmonary artery. Occasionally, a chronic venous disease may be present which causes problems. In these circumstances, the fluid will collect from the inferior vena cava rather than the pulmonary artery. These are called intraluminal infusionations and have excellent results.

Although this technology has existed for decades, there have been very few clinical trials on the use of an infantally invasive graft for treating childhood diseases like encephalopathy or lymphatic deficiency. But, there was a recent report of success for a patient with an infantile hemophilia virus disease who was given this graft. Other experimental approaches to treat peripheral tolerance comprise a combination of interferon gamma treatment, radioactive therapy, radiofrequency ablation and balloon catheters. All of these procedures have shown promising effects in certain patients but to date there are no published studies reporting success for all of these treatments.